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Rheumatology

Is a non-surgical subspecialty that is devoted to diagnosis and therapy of rheumatic diseases. It focuses on common and complex problems that may affect the entire body, and frequently involves the musculoskeletal system. Diseases include rheumatoid arthritis, gout, lupus, osteoporosis, fibromyalgia and spondylitis.

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Ankylosing spondylitis

Ankylosing spondylitis is a chronic inflammatory disease of the axial skeleton with variable involvement of peripheral joints and nonarticular structures. AS is a form of spondyloarthritis, a chronic, inflammatory arthritis and autoimmune disease. It mainly affects joints in the spine and the sacroiliac joint in the pelvis, and can cause eventual fusion of the spine.

It is a member of the group of the spondyloarthropathies with a strong genetic predisposition. Complete fusion results in a complete rigidity of the spine, a condition known as “bamboo spine”.

Fibromyalgia

Fibromyalgia is a common health problem that causes widespread pain and tenderness (sensitive to touch). The pain and tenderness tend to come and go, and move about the body. Most often, people with this chronic (long-term) illness are fatigued (very tired) and have sleep problems. It can be hard to diagnose fibromyalgia.

Gout

Is a medical condition usually characterized by recurrent attacks of acute inflammatory arthritis—a red, tender, hot, swollen joint. The metatarsal-phalangeal joint at the base of the big toe is the most commonly affected (approximately 50% of cases). However, it may also present as tophi, kidney stones, or urate nephropathy. It is caused by elevated levels of uric acid in the blood which crystallizes and the crystals are deposited in joints, tendons, and surrounding tissues.

Gout has increased in frequency in recent decades affecting approximately one to two percent of the Western population at some point in their lives. The increase is believed to be due to increasing risk factors in the population, such as metabolic syndrome, longer life expectancy and changes in diet. Gout was historically known as “the disease of kings” or “rich man’s disease”.

Lupus

An autoimmune inflammatory disease of the connective tissues, occurring mainly among middle-aged women, chiefly characterized by skin eruptions, joint pain, recurrent pleurisy, and kidney disease

No one knows what causes lupus. Scientists think that people are born with the genes to develop lupus and that something triggers the disease and symptoms.

Osteoarthritis

Also known as degenerative arthritis or degenerative joint disease or osteoarthrosis, is a group of mechanical abnormalities involving degradation of joints, including articular cartilage and subchondral bone. Symptoms may include joint pain, tenderness, stiffness, locking, and sometimes an effusion. A variety of causes—hereditary, developmental, metabolic, and mechanical—may initiate processes leading to loss of cartilage. When bone surfaces become less well protected by cartilage, bone may be exposed and damaged. As a result of decreased movement secondary to pain, regional muscles may atrophy, and ligaments may become more lax.

Pain management

Is a branch of medicine employing an interdisciplinary approach for easing the suffering and improving the quality of life of those living with pain. The typical pain management team includes medical practitioners, clinical psychologists, physiotherapists, occupational therapists, and nurse practitioners. Pain sometimes resolves promptly once the underlying trauma or pathology has healed, and is treated by one practitioner, with drugs.

Polymyalgia rheumatica

(sometimes referred to as PMR) is a common cause of widespread aching and stiffness in older adults. Because PMR does not often cause swollen joints, it may be hard to recognize. PMR may occur with another health problem, giant cell arteritis.

Facts

  • PMR affects adults over the age of 50.
  • Aching and stiffness in PMR affect the upper arms, neck, buttocks and thighs, and are most severe in the morning.
  • These symptoms respond quickly and completely to low doses of corticosteroids.

Polymyositis

Polymyositis is an idiopathic inflammatory myopathy that causes symmetrical, proximal muscle weakness; elevated skeletal muscle enzyme levels; and characteristic electromyography (EMG) and muscle biopsy findings

Psoriatic arthritis

Psoriatic arthritis is a type of arthritic inflammation that occurs in about 15 percent of patients who have a skin rash called psoriasis. This particular arthritis can affect any joint in the body, and symptoms vary from person to person. Research has shown that persistent inflammation from psoriatic arthritis can lead to joint damage. Fortunately, available treatments are effective for most people.

Facts

  • Early diagnosis is important to avoid damage to joints.
  • Psoriatic arthritis can occur in people without skin psoriasis, particularly in those who have relatives with psoriasis.
  • Physical activity helps maintain joint movement.

Rheumatoid arthritis

Is a chronic, systemic inflammatory disorder that may affect many tissues and organs, but principally attacks flexible (synovial) joints. The process produces an inflammatory response of the capsule around the joints. The pathology of the disease process often leads to the destruction of articular cartilage and ankylosis of the joints.

About 1% of the world’s population is afflicted by rheumatoid arthritis, women three times more often than men. Onset is most frequent between the ages of 40 and 50, but people of any age can be affected. It can be a disabling and painful condition, which can lead to substantial loss of functioning and mobility if not adequately treated. It is a clinical diagnosis made on the basis of symptoms, physical exam, radiographs (X-rays) and labs, although the American College of Rheumatology (ACR) diagnostic guidelines.

Sjögren’s syndrome

Sjögren’s syndrome is an inflammatory disease that can affect many different parts of the body, but most often affects the tear and saliva glands. Patients with this condition may notice irritation, a gritty feeling, or painful burning in the eyes. Dry mouth (or difficulty eating dry foods) and swelling of the glands around the face and neck are also common. Some patients experience dryness in the nasal passages, throat, vagina and skin. Swallowing difficulty and symptoms of acid reflux are also common.

Facts

  • Sjögren’s syndrome sometimes develops as a complication of another autoimmune disorder.
  • Symptoms vary in type and intensity, but many people with Sjögren’s are able to live normal lives.
  • Regular medical care is important.

Vasculitis

Vasculitis refers to inflammation of the blood vessels. Vasculitis can result in poor blood flow to tissues throughout the body, such as the lungs, nerves and skin. Thus, vasculitis has a wide range of signs and symptoms , such as:

  • Shortness of breath and cough
  • Numbness or weakness in a hand or foot
  • Red spots on the skin (“purpura”), lumps (“nodules”) or sores (“ulcers”) On the other hand, vasculitis of the kidneys may produce no symptoms at first but is still a serious problem.
  • Vasculitis can be mild or disabling, or even lead to death. Patients can have one episode of vasculitis or have repeated episodes over several years. Most types of vasculitis are rare.

Scientific research

The field of osteoimmunology has emerged to further examine the interactions between the immune system, joints and bones. Epidemiological studies and medication trials are also being conducted. Scientific research on biologics and clinical trials on monoclonal antibody therapies have added a new dimension to the medical treatment of arthritic disorders.